The march was organised by National Action Alliance, a civil rights group headed by the Rev. Al Sharpton
Thousands of demonstrators gathered in Washington for a march to protest the killings of unarmed black men by law enforcement officers and to urge policymakers to do more to protect African-Americans from unjustified police violence.
Organisers said the event and a parallel march in New York City would rank among the largest in the recent wave of protests against the killings of black males by officers in Ferguson, Missouri, New York, Cleveland and elsewhere.
Decisions by grand juries to return no indictments against the officers involved in the death of Michael Brown in Missouri and Eric Garner in New York have put the issue of police treatment of minorities back on the national agenda.
Thousands of people assembled in Freedom Plaza near the White House, before setting off on a three-mile march down Pennsylvania Avenue for a rally in front of the US Capitol.
The march was organised by National Action Alliance, a civil rights organisation headed by the Rev. Al Sharpton.
“We need more than just talk,” he said in a statement before the march. “We need legislative action that will shift things both on the books and in the streets.”
Rev Sharpton urged Congress to pass legislation that would allow federal prosecutors to take over cases involving police.
He said local district attorneys often work with police regularly, raising the potential of conflicts of interest when prosecutors investigate incidents.
The Washington protest included the families of Eric Garner and Akai Gurley, who were killed by New York police; Trayvon Martin, slain by a Florida neighbourhood watchman in 2012; and Michael Brown, killed by an officer in Ferguson.
Samaria Rice, the mother of 12-year-old Tamir Rice, shot to death last month by a Cleveland police officer, also attended.
Protesters arrived by bus from as far away as Florida, Connecticut and Pittsburgh, according to the organisers’ website.
In New York, the march was expected to draw about tens of thousands of people and was meant to reinvigorate protests that swelled after a grand jury declined to indict the officer who killed Eric Garner using a chokehold, organisers said.
“It’s open season on black people now,” New York march co-organiser Umaara Elliott said in a statement.
“So we demand that action be taken at every level of government to ensure that these racist killings by the police cease.”